Modeling of Hypoxic Brain Injury through 3D Human Neural Organoids
نویسندگان
چکیده
منابع مشابه
P 104: Effects of Human Neural Stem Cells in Cure Neuroinflammation of Traumatic Brain Injury
Traumatic brain injury (TBI) is defined as an external mechanical injury to the brain. Neuroinflammation plays a vital role in the pathophysiology of TBI. Microglia and astrocytes play a central role in the initiation and regulation of inflammation. Numerous pro-inflammatory mediators including cytokines, chemokines, reactive oxygen species (ROS) and nitric oxide (NO) released by microglia. In ...
متن کاملO14: Application of Neural Stem Cells Derived from Human Meningioma in Traumatic Brain Injury
Traumatic brain injury is considered as one of the main causes of morbidity and mortality worldwide. Apart from primary mechanical injury, Secondary injuries due to inflammation and apoptosis result in great neuronal damage. Current treatments are not able to regenerate the damaged part and prevent future sequels. Using human stem cells with self-assembling scaffolds may be promising in treatme...
متن کاملP6: Application of 3D Bioactive Scaffolds in Brain Injury
لطفاً به چکیده انگلیسی مراجعه شود.
متن کاملTranslational potential of human brain organoids
The recent technology of 3D cultures of cellular aggregates derived from human stem cells have led to the emergence of tissue-like structures of various organs including the brain. Brain organoids bear molecular and structural resemblance with developing human brains, and have been demonstrated to recapitulate several physiological and pathological functions of the brain. Here we provide an ove...
متن کاملNeural injury of the Papez circuit following hypoxic–ischemic brain injury
INTRODUCTION Hypoxic-ischemic brain injury (HI-BI), a result of oxygen deprivation of the brain, is accompanied by memory impairment. In this study, we report on a patient with neural injury of the Papez circuit following HI-BI, demonstrated by diffusion tensor tractography (DTT). CLINICAL FINDINGS/PATIENT CONCERNS A 48-year-old male patient suffered spontaneous cardiopulmonary arrest and und...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Cells
سال: 2021
ISSN: 2073-4409
DOI: 10.3390/cells10020234